AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA], Biotinylated
- Cat.Number : AS-29945-1
- Manufacturer Ref. :
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The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 µM). It also competitively inhibits histone H2B phosphorylation (Ki = 12 µM) by AKT.
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Citations
Pim kinase substrate identification and specificity.
J. Biochem. . 2007 Jan 18 ; 141(3) 353 | DOI : 10.1093/jb/mvm040
- C. Peng
References
AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation
Ann Rev Biochem . 1999 Jul 01 ; 68(1) 965 | DOI : https://doi.org/10.1146/annurev.biochem.68.1.965
- TO. Chan
- et al
Peptide and Protein Library Screening Defines Optimal Substrate Motifs for AKT/PKB
JBC . 2000 Nov 01 ; 275(46) 36108 | DOI : https://doi.org/10.1074/jbc.M005497200
- T. Obata
- et al