Peptides

Aminopeptidase N Ligand (CD13), NGR peptide - 5 mg

$599.00
Check your price
  • Cat.Number : AS-60171-5
  • Availability :
    In stock

Quantity

The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.

Specifications

Chemistry
Sequence one letter code
  • CNGRCG (Disulfide bridge: 1-5)
Sequence three letter code
  • H-Cys-Asn-Gly-Arg-Cys-Gly-OH (Disulfide bridge: 1-5)
Molecular Formula
  • C20H36N10O8S2
Molecular Mass/ Weight
  • 606.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

You may also be interested in the following product(s)

IMG-EN-AS-61204-01.jpg

(Arg)9 - 1 mg

Cat.Number : AS-61204
$81.00 Excl. Tax
IMG-EN-AS-24175-01.jpg

FITC-LC-Antennapedia Peptide

Cat.Number : AS-24175
$198.00 Excl. Tax
IMG-EN-AS-61211-01.jpg

TAT (47-57), TAMRA-labeled - 1 mg

Cat.Number : AS-61211
$283.00 Excl. Tax

References

Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.

Cancer Res. . 2002 Feb 01 ; 62(3) 867 | DOI : PMID: 11830545

  • F. Curnis
  • et al

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration.

J Clin Invest. . 2002 Aug 01 ; 110(4) 475 | DOI : 10.1172/JCI15223

  • F. Curnis