Aminopeptidase N Ligand (CD13), NGR peptide - 5 mg
- Cat.Number : AS-60171-5
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The NGR (Asn-Gly-Arg) peptide motif is an aminopeptidase N (CD13) ligand that targets angiogenic blood vessels. NGR-containing peptides have been proven useful for delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.
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References
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.
Cancer Res. . 2002 Feb 01 ; 62(3) 867 | DOI : PMID: 11830545
- F. Curnis
- et al
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration.
J Clin Invest. . 2002 Aug 01 ; 110(4) 475 | DOI : 10.1172/JCI15223
- F. Curnis