Peptides
(Arg)9 - 1 mg
$66.00
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- Cat.Number : AS-61204
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(Arg)9 is a cell-permeable peptide used for drug delivery. It has been shown that poly-Arg peptides composed of 9 arginine residues are able to efficiently translocate across cells. It has also been shown in model systems that Arg-9 translocation involves nucleation of transient pores enabling flow of ions across the membrane, and that it's electrostatic attraction to the phosphate groups of membranes is a key property for its translocation.
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References
Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell-Penetrating Peptides
Biophys J . 2009 Oct 07 ; 97(7) 1917 | DOI : 10.1016/j.bpj.2009.05.066
- HD. Herce
- et al