IMG-EN-AS-61204-01.jpg
Peptides

(Arg)9 - 1 mg

$66.00
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  • Cat.Number : AS-61204
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(Arg)9 is a cell-permeable peptide used for drug delivery. It has been shown that poly-Arg peptides composed of 9 arginine residues are able to efficiently translocate across cells. It has also been shown in model systems that Arg-9 translocation involves nucleation of transient pores enabling flow of ions across the membrane, and that it's electrostatic attraction to the phosphate groups of membranes is a key property for its translocation.

Specifications

Chemistry
Sequence one letter code
  • RRRRRRRRR
Sequence three letter code
  • H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH
CAS registry number
  • 143413-47-2
Molecular Formula
  • C54H110N36O10
Molecular Mass/ Weight
  • 1423.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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References

Arginine-Rich Peptides Destabilize the Plasma Membrane, Consistent with a Pore Formation Translocation Mechanism of Cell-Penetrating Peptides

Biophys J . 2009 Oct 07 ; 97(7) 1917 | DOI : 10.1016/j.bpj.2009.05.066

  • HD. Herce
  • et al