Peptides

Cell Permeable-Mastoparan Peptide

  • Cat.Number : AS-24270
  • Availability :
    In stock

Size

Quantity

This 14-residue peptide toxin from the wasp venom is originally found as a histamine releaser from mast cells. It induces mitochondrial membrane permeabilization via a CsA-inhibitable mechanism.

Specifications

Chemistry
Sequence one letter code
  • INLKALAALAKKIL-NH2
Sequence three letter code
  • H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
CAS registry number
  • 72093-21-1
Molecular Formula
  • C70H131N19O15
Molecular Mass/ Weight
  • 1479
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Wasp

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References

Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers.

Eur J Biochem . 2003 Sep 15 ; 268 302 | DOI : https://doi.org/10.1046/j.1432-1033.2001.01880.x

  • Y. Hori
  • et al

Identification of a 97-kDa mastoparan-binding protein involving in Ca(2+) release from skeletal muscle sarcoplasmic reticulum.

Mol Pharmacol. . 2000 Jun 01 ; 57(6) 1235 | DOI : PMID: 10825395

  • Y. Hirata
  • et al

Mastoparan-stimulated prolactin secretion in rat pituitary GH3 cells involves activation of Gq/11 proteins.

Endocrinology. . 1997 May 01 ; 138(5) 1949 | DOI : 10.1210/endo.138.5.5111

  • Y. Yajima
  • et al

A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation.

Biochemistry. . 1997 Mar 25 ; 36(12) 3632 | DOI : 10.1021/bi962356m

  • M. Sukumar
  • et al