Apelin-16, human, bovine - 1 mg
- Cat.Number : AS-63699
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Apelin is the endogenous ligand for the G-protein-coupled APJ receptor. It is produced as a pre-proprotein of 77 amino acids. Upon signal peptide cleavage, the proprotein of 55 amino acids may generate several active fragments: Apelin-36 (36 aa corresponding to the sequence 42-77), Apelin-17 (17 aa corresponding to the sequence 61-77) and Apelin-13 (13 aa corresponding to the sequence 65-77). Apelin-13 may undergo a pyroglutamylation at its N-terminal glutamine residue.
Apelin-16 corresponds to amino acids 62-77.
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References
Regulation of feeding behavior, gastrointestinal function and fluid homeostasis by apelin
Peptides . 2013 Jun 01 ; 44 87 | DOI : https://doi.org/10.1016/j.peptides.2013.03.024
- S-Y. Lv
- et al