Peptides

[Arg(Me2s)8]-Histone H3 (1-21)-K(Biotin) - 1 mg

$379.00
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  • Cat.Number : AS-65351-1
  • Availability :
    In stock

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This is histone H3 (1-21) symmetrically dimethylated at Arg8 with a methyl group added to each nitrogen of the guanidinium group. This peptide is biotinylated at the epsilon side chain of an additional C-terminal Lys. Methylation at Arg8 blocks G9a methylation of Lys9. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • ARTKQTA-R(Me2s)-KSTGGKAPRKQLA-K(Biotin)
Sequence three letter code
  • H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg(Me2s)-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2637.3
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

PELP1 oncogenic functions involve CARM1 regulation.

Carcinogenesis . 2013 Mar 13 ; 34(7) 1468 | DOI : 10.1093/carcin/bgt091

  • M. Mann

References

Protein lysine methyltransferase G9a acts on non-histone targets

Nat Chem Biol . 2008 Jun 01 ; 4(6) 344 | DOI : 10.1038/nchembio.88

  • P. Rathert
  • et al