Peptides

Histone H3 (21-44)-GK(Biotin)

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  • Cat.Number : AS-64440-025
  • Availability :
    In stock

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This peptide is derived from Histone H3 21-44 amino acids, with additional glycine and lysine at the C-terminus with lysine biotinylated and used as substrate in methylation assays.

Specifications

Chemistry
Sequence one letter code
  • ATKAARKSAPATGGVKKPHRYRPG-GK(Biotin)
Sequence three letter code
  • H-Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin)-OH
Molecular Formula
  • C127H214N44O33S1
Molecular Mass/ Weight
  • 2917.6
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.

PLOS Genet . 2012 May 17 ; 8(5) e1002717 | DOI : 10.1371/journal.pgen.1002717

  • MM. Pradeepa

Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening.

JBS . 2016 Sep 27 ; 21(10) 1075 | DOI : 10.1177/1087057116667255

  • DS. Auld

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H327 methylated nucleosomes in brain.

Nucl Acids Res . 2011 Dec 05 ; 40(7) 2884 | DOI : 10.1093/nar/gkr1066.

  • AA. Thambirajah

References

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain

Nucl Acids Res . 2012 Apr 01 ; 40(7) 2884 | DOI : https://doi.org/10.1093/nar/gkr1066

  • AA. Thambirajah
  • et al