Peptides

[Lys(Ac)5/8/12/16]-Histone H4 (1-21)-GGK(Biotin) - 1 mg

$417.00
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  • Cat.Number : AS-64989-1
  • Availability :
    In production

Quantity

This peptide is histone H4 (1-21), acetylated at lysine 5, 8, 12, and 16. It contains a C-terminal GG linker, followed by a biotinylated Lys. In general, histone H4 acetylation is associated with increased DNA replication during mitosis, although different combinations of acetylation at specific sites are selective for specific processes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHRKV-GGK(Biotin)
Sequence three letter code
  • H-Ser-Gly-Arg-Gly-Lys(Ac)-Gly-Gly-Lys(Ac)-Gly-Leu-Gly-Lys(Ac)-Gly-Gly-Ala-Lys(Ac)-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2728.3
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Distinctive patterns of histone H4 acetylation are associated with defined sequence elements within both heterochromatic and euchromatic regions of the human genome

Nucl Acids Res . 1998 Feb 01 ; 26(4) 994 | DOI : https://doi.org/10.1093/nar/26.4.994

  • C. Johnson
  • et al

Histone H4 Acetylation of Euchromatin and Heterochromatin Is Cell Cycle Dependent and Correlated with Replication Rather Than with Transcription

Plant Cell . 2000 Nov 01 ; 12(11) 2087 | DOI : https://doi.org/10.1105/tpc.12.11.2087

  • Z. Jasencakova
  • et al