b-casomorphin (1-7), bovine - 1 mg
- Cat.Number : AS-61124
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b-Casomorphin-7 is a milk opioid peptide derived from fragment 60-66 of bovine beta-Casein. It strongly stimulates mucin secretion in the rat jejunum through a nervous pathway and mu-opioid receptor activation. The presence of the Tyr-Pro aromatic sequence makes the peptide selective for the mu receptor while the high contents of proline residues in the sequence makes the peptide resistant to degradation by gastrointestinal enzymes.
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References
b-Casomorphin-7 regulates the secretion and expression of gastrointestinal mucins through a -opioid pathway
Am J Physiol - Gastrointestinal Liver Physiol . 2005 Dec 15 ; 290 G1105 | DOI : 10.1152/ajpgi.00455.2005.
- S. Zoghbi
- et al
Milk Bioactive Peptides and β-Casomorphins Induce Mucus Release in Rat Jejunum
Am J Nutrition . 2003 Nov 01 ; 133(11) 3499 | DOI : https://doi.org/10.1093/jn/133.11.3499
- A. Trompette
- et al
Novel Opioid Peptides Derived from Casein (β-Casomorphins). I. Isolation from Bovine Casein Peptone
Hoppe Seylers Z Physiol Chem . 1979 Sep 01 ; 360(9) 1211 | DOI : 10.1515/bchm2.1979.360.2.1211
- V. Brantl
- et al