Peptides

Bak BH3 (72-87), TAMRA-labeled - 1 mg

$256.00
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  • Cat.Number : AS-64590
  • Availability :
    In production

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This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. This peptide is labeled with 5-TAMRA on the N-terminus, Abs/Em= 541/568 nm

Specifications

Chemistry
Sequence one letter code
  • 5-TAMRA-GQVGRQLAIIGDDINR
Sequence three letter code
  • 5-TAMRA-Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg-OH
Molecular Formula
  • C97H145N27O28
Molecular Mass/ Weight
  • 2137.5
Properties
Absorbance (nm)
  • 541
Emission (nm)
  • 568
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells

Cancer Res . 2000 Mar 01 ; 60(6) 1498 | DOI : 10749111

  • J. Wang
  • et al

c-Myc functionally cooperates with Bax to induce apoptosis

Mol Cell Biol . 2002 Sep 01 ; 22(17) 6158 | DOI : 10.1128/MCB.22.17.6158-6169.2002

  • P. Juin
  • et al