IMG-EN-AS-64082-01.jpg
Peptides

Bcl-2 Binding Peptide, Bad BH3 Peptide - 1 mg

$242.00
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  • Cat.Number : AS-64082
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This is a bcl-2 binding peptide. This peptide is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165.

Specifications

Chemistry
Sequence one letter code
  • LWAAQRYGRELRRMSDEFEGSFKGL
Sequence three letter code
  • H-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-H-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
Molecular Formula
  • C133H204N40O38S1
Molecular Mass/ Weight
  • 3003.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse, rat

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Citations

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins.

PNAS . 2008 Dec 23 ; 105(51) 20327 | DOI : 10.1073/pnas.0808036105

  • J. Chipuk

References

BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia

Blood . 2008 Feb 15 ; 111(4) 111(4) | DOI : https://doi.org/10.1182/blood-2007-06-098012

  • V. Del Gaizo Moore
  • et al