Peptides

BMAP-18

$182.00
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  • Cat.Number : AS-65597
  • Availability :
    In stock

Quantity

BMAP-18 is a truncated form of the antimicrobial peptide BMAP-27. Bovine myeloid antimicrobial peptide-27 (BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of its decreased hemolytic activity and retained antimicrobial activity.

Specifications

Chemistry
Sequence one letter code
  • GRFKRFRKKFKKLFKKLS
Sequence three letter code
  • H-Gly-Arg-Phe-Lys-Arg-Phe-Arg-Lys-Lys-Phe-Lys-Lys-Leu-Phe-Lys-Lys-Leu-Ser-OH
Molecular Formula
  • C113H188N34O20
Molecular Mass/ Weight
  • 2343
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Bovine

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References

Cell selectivity, mechanism of action and LPS-neutralizing activity of bovine myeloid antimicrobial peptide-18 (BMAP-18) and its analogs

Peptides . 2011 Jun 01 ; 32(6) 1123 | DOI : https://doi.org/10.1016/j.peptides.2011.03.024

  • EK. Lee
  • et al

Killing of trypanosomatid parasites by a modified bovine host defense peptide, BMAP-18

PLoS Negl Trop Dis . 2009 Feb 03 ; 3(2) 373 | DOI : https://doi.org/10.1371/journal.pntd.0000373

  • L. Haines
  • et al