BMAP-18
- Cat.Number : AS-65597
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BMAP-18 is a truncated form of the antimicrobial peptide BMAP-27. Bovine myeloid antimicrobial peptide-27 (BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of its decreased hemolytic activity and retained antimicrobial activity.
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References
Cell selectivity, mechanism of action and LPS-neutralizing activity of bovine myeloid antimicrobial peptide-18 (BMAP-18) and its analogs
Peptides . 2011 Jun 01 ; 32(6) 1123 | DOI : https://doi.org/10.1016/j.peptides.2011.03.024
- EK. Lee
- et al
Killing of trypanosomatid parasites by a modified bovine host defense peptide, BMAP-18
PLoS Negl Trop Dis . 2009 Feb 03 ; 3(2) 373 | DOI : https://doi.org/10.1371/journal.pntd.0000373
- L. Haines
- et al