C34, gp41 HIV Fragment - 1 mg
- Cat.Number : AS-62101
- Manufacturer Ref. :
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This C34 peptide, also known as HR2, belongs to the helical region of gp41 of HIV, C-terminal heptad repeat 2 (HR2) defined as C helix or C peptide. It is known that HIV-1 enters cells by membrane fusion, C34 gp41 peptide is a potent inhibitors of HIV-1 fusion.
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References
Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection
PNAS . 2005 Jul 21 ; 102 12903 | DOI : https://doi.org/10.1073/pnas.0502449102
- E. Bianchi
- et al
Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion
PNAS . 2006 Jul 24 ; 103 13938 | DOI : https://doi.org/10.1073/pnas.0601036103
- G. Frey
- et al
Binding of the 2F5 Monoclonal Antibody to Native and Fusion-Intermediate Forms of Human Immunodeficiency Virus Type 1 gp41: Implications for Fusion-Inducing Conformational Changes
J Virol . 2004 Mar 01 ; 78 2627 | DOI : 10.1128/JVI.78.5.2627-2631.2004
- E. Rosny
- et al