IMG-EN-AS-65121-01.jpg
Peptides

C5a Receptor Agonist, mouse, human - 1 mg

$103.00
Check your price
  • Cat.Number : AS-65121
  • Availability :
    In stock

Alternative choices

Quantity

Add to wishlist Bulk Quote

This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer.

Specifications

Chemistry
Sequence one letter code
  • FKP-(D-Cha)-Cha-r
Sequence three letter code
  • H-Phe-Lys-Pro-D-Cha-Cha-D-Arg-OH
Molecular Mass/ Weight
  • 853.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse, human

Downloads

You may also be interested in the following product(s)

IMG-EN-AS-61119-01.jpg

[Trp63, 64]-C3a (63-77) - 1 mg

Cat.Number : AS-61119
$134.00 Excl. Tax
IMG-EN-AS-61118-01.jpg

C3a (70-77) - 1 mg

Cat.Number : AS-61118
$55.00 Excl. Tax
IMG-EN-AS-65122-01.jpg

C5a Receptor Antagonist, linear, human, rat - 1 mg

Cat.Number : AS-65122
$127.00 Excl. Tax

References

Comparative Agonist/Antagonist Responses in Mutant Human C5a Receptors Define the Ligand Binding Site

J Biol Chem . 2005 May 01 ; 280(18) 17831 | DOI : https://doi.org/10.1074/jbc.M410797200

  • A. Higginbottom
  • et al

Disulfide trapping to localize small-molecule agonists and antagonists for a G protein-coupled receptor

PNAS . 2005 Feb 22 ; 102(8) 2719 | DOI : https://doi.org/10.1073/pnas.0500016102

  • E. Buck
  • J. Wells