Peptides

Calcitonin Gene Related Peptide, CGRP (alpha), human, Biotin-LC-labeled - 1 mg

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  • Cat.Number : AS-64564-1
  • Availability :
    In stock

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This is Calcitonin Gene Related Peptide, CGRP (alpha), human peptide with biotin on the N-terminus via a linker (LC, long chain, 6-amidohexanoyl). CGRP is a 37-amino acid neuropeptide produced by tissue specific processing of the calcitonin gene and is the major product in neural tissues. CGRP is released by motor neurons where it exerts both short and long term effects on skeletal muscle fibers. In addition, sensory neurons release CGRP to the surrounding vaculature where it is partly responsible for local vasodilation following mucle contraction. CGRP acts through G protein-coupled receptors whose presence and changes in function modulate the peptide's effects in various tissues.

Specifications

Chemistry
Sequence one letter code
  • Biotin-LC-ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (Disulfide bridge:2-7)
Sequence three letter code
  • Biotin-LC-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge:2-7)
Molecular Mass/ Weight
  • 4129
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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