Calcitonin, human
- Cat.Number : AS-20673
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Human calcitonin reduces blood calcium, opposing the effects of parathyroid hormone (PTH). It stimulates cyclic nucleotide accumulation in human kidney cortex and medulla. Calcitonin maybe involved in osteoporosis and in Paget's disease.
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References
Mechanism of action of human calcitonin gene-related peptide in rabbit heart and in human mammary arteries.
J Cardiovas Pharmacol . 1997 Apr 01 ; 29(4) 463 | DOI : 10.1097/00005344-199704000-00006
- R. Raddino
- et al
Human calcitonin increases both cyclic AMP and cyclic GMP accumulation in human kidney cells
Eur J Pharmacol . 1985 Jan 08 ; 107(3) 347 | DOI : https://doi.org/10.1016/0014-2999(85)90260-2
- C. Rotella
- et al
A Role for the C-Terminus of Calcitonin in Aggregation and Gel Formation: A Comparative Study of C-Terminal Fragments of Human and Salmon Calcitonin
Biochem Biophys Res Commun . 1998 Apr 17 ; 245(2) 344 | DOI : https://doi.org/10.1006/bbrc.1998.8425
- D. Moriarty
- et al
Expression Cloning and Receptor Pharmacology of Human Calcitonin Receptors from MCF-7 Cells and Their Relationship to Amylin Receptors
Mol Pharmacol. . 1997 Dec 01 ; 52(6) 1164 | DOI : 10.1124/mol.52.6.1164
- W. Chen
- et al