Peptides

[Cit26]-Histone H3 (21-44)-GGK(Biotin) - 1 mg

$362.00
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  • Cat.Number : AS-65234-1
  • Availability :
    In stock

Quantity

This peptide is histone H3 (21-44) with deimination at Arg26, converting it to Cit (citrulline). It is biotinylated through a C-terminal GGK linker. Deimination by peptidyl arginine deiminase 4 (PADI4) blocks methylation by the CARM1 methyltransferase and inhibits transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • ATKAA-Cit-KSAPATGGVKKPHRYRPG-GGK(Biotin)
Sequence three letter code
  • H-Ala-Thr-Lys-Ala-Ala-Cit-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2975.6
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

PELP1 oncogenic functions involve CARM1 regulation.

Carcinogenesis . 2013 Mar 13 ; 34(7) 1468 | DOI : 10.1093/carcin/bgt091

  • M. Mann

References

Histone Deimination Antagonizes Arginine Methylation

Cell . 2004 Sep 03 ; 118(5) 545 | DOI : https://doi.org/10.1016/j.cell.2004.08.020

  • G. Cuthbert
  • et al