Peptides

[Cit3]-Histone H4 (1-23)-GGK(Biotin) - 1 mg

$417.00
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  • Cat.Number : AS-65275-1
  • Availability :
    In stock

Quantity

This peptide is histone H4 (1-23) with deimination at Arg3. It contains a C-terminal GGK linker with biotinylation on the side chain of this Lys. Deimination of Arg3 to Cit is carried out by peptidylarginine deiminase (PADI)-4. Although the function of deimination is not clearly known, it has been shown to inhibit Arg methylation and repress nuclear hormone receptor-dependent gene activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • SG-Cit-GKGGKGLGKGGAKRHRKVLR-GGK(Biotin)
Sequence three letter code
  • H-Ser-Gly-Cit-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2830.5
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Deimination of Histone H2A and H4 at Arginine 3 in HL-60 Granulocytes

Biochem . 2005 Mar 19 ; 44(15) 5827 | DOI : https://doi.org/10.1021/bi047505c

  • T. Hagiwara
  • et al