IMG-EN-AS-60510-5-01.jpg
Peptides

CREBtide [KRREILSRRPSYR] - 5 mg

$610.00
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  • Cat.Number : AS-60510-5
  • Availability :
    In stock

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CREBtide is a synthetic substrate for PKA (Km = 3.9 µM). This peptide is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).

Specifications

Chemistry
Sequence one letter code
  • KRREILSRRPSYR
Sequence three letter code
  • H-Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH
CAS registry number
  • 149155-45-3
Molecular Formula
  • C73H129N29O19
Molecular Mass/ Weight
  • 1717.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat, bovine, zebrafish

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References

Active catalytic fragment of Ca2+/calmodulin-dependent protein kinase II. Purification, characterization, and structural analysis

JBC . 1991 Aug 01 ; 266(23) 15391 | DOI : https://doi.org/10.1016/S0021-9258(18)98628-X

  • Y. Yamagata
  • et al

An Extranuclear Locus of cAMP-Dependent Protein Kinase Action Is Necessary and Sufficient for Promotion of Spiral Ganglion Neuronal Survival by cAMP

J Neurosci . 2003 Feb 01 ; 23(3) 777 | DOI : https://doi.org/10.1523/JNEUROSCI.23-03-00777.2003

  • J. Bok
  • et al

cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates Δ-CREB, and a synthetic Δ-CREB peptide

Biochem Cell Biol . 1992 Oct 01 ; 70 1277 | DOI : https://doi.org/10.1139/o92-174

  • JL. Colbran
  • et al