[Des-octanoyl]-Ghrelin, human - 1 mg
- Cat.Number : AS-61177
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Des-octanoyl (or Des-acyl) Ghrelin is the unacylated precursor peptide to Ghrelin. Des-octanoyl Ghrelin is converted to Ghrelin by the enzymic addition of an octanyl group. Studies indicate that the amount of Des-octanoyl Ghrelin in the circulation is approximately 20 fold higher than that of Ghrelin. Des-octanoyl Ghrelin is not an agonist of the Ghrelin growth hormone receptor 1a (GHSR1a).
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Citations
Ghrelin treatment protects lactotrophs from apoptosis in the pituitary of diabetic rats.
Mol Cell Endocrinol . 2009 Jun 18 ; 309(1-2) 67 | DOI : 10.1016/j.mce.2009.06.006
- M. Granado
References
Hypotensive effects of ghrelin receptor agonists mediated through a novel receptor
Br J Pharmacol . 2014 Mar 01 ; 171(5) 1275 | DOI : https://doi.org/10.1111/bph.12527
- B. Callaghan
- et al