Dynorphin A (1-17) Peptide Fragment
- Cat.Number : AS-24297
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Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. Upon cleavage by proprotein convertase 2 (PC2), multiple active peptides are released: dynorphin A, dynorphin B, and α/β-neo-endorphin. Dynorphins exert their effects primarily through the Κ-opioid receptor (KOR), a G-protein-coupled receptor. Dynorphin has been shown to be a modulator of pain response, involved in drug addiction and appetite control.
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Citations
Parallel detection of intrinsic fluorescence from peptides and proteins for quantification during mass spectrometric analysis
Anal Chem . 2011 Mar 15 ; 83(6) 2187 | DOI : 10.1021/ac103023q
- J. Russell
References
Porcine pituitary dynorphin: complete amino acid sequence of the biologically active heptadecapeptide
PNAS . 1981 Nov 01 ; 78(11) 7219 | DOI : https://doi.org/10.1073/pnas.78.11.7219
- A. Goldstein
- et al
Isolation and structure of dynorphin, an opioid peptide, from porcine duodenum.
Nature . 1982 Jan 28 ; 295 339 | DOI : 10.1038/295339a0
- S. Tachibana
- et al