Peptides
Endothelin 1, human, FAM-labeled - 0.5 mg
$850.00
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- Cat.Number : AS-27116
- Manufacturer Ref. :
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This is a fluorescent (FAM)-labeled peptide, Abs/Em = 494/521 nm. Endothelin-1 (ET-1) is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes.
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