Ghrelin, human, Biotin-labeled - 1 mg
- Cat.Number : AS-29391
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This Ghrelin peptide is biotinylated at the peptide N-terminus. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.
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References
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Nature . 1999 Dec 09 ; 402(6762) 656 | DOI : https://doi.org/10.1038/45230
- M. Kojima
- et al
Ghrelin signalling on food reward: a salient link between the gut and the mesolimbic system
J Neuroendocrinol . 2015 Jun 01 ; 27(6) 424 | DOI : 10.1111/jne.12236
- M. Perello
- SL. Dickson
Ghrelin: structure and function
Physiol Rev . 2005 Apr 01 ; 85(2) 495 | DOI : https://doi.org/10.1152/physrev.00012.2004
- M. Kojima
- K. Kangawa
Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone
Cell . 2008 Feb 08 ; 132(3) 387 | DOI : https://doi.org/10.1016/j.cell.2008.01.017
- J. Yang
- et al