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Peptides

Histone H4 (1-21), p300/CBP Substrate - 1 mg

$226.00
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  • Cat.Number : AS-62499
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This sequence is amino acids 1 to 21 fragment of the histone 4. Histone acetyltransferase (HAT) p300/CBP catalyses the acetylation of this N-terminal tail of free histone H4 at Lys5, 8, 12, 16. Lys8 is thought to be the preferred acetylation site in H4. Determinants of interaction of p300 with histone 4 appear to be fully present on H4-21, the N-terminal region of the protein.

Specifications

Chemistry
Sequence one letter code
  • SGRGKGGKGLGKGGAKRHRKV
Sequence three letter code
  • H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-OH
Molecular Formula
  • C87H159N37O23
Molecular Mass/ Weight
  • 2091.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

DNA Damage-Induced Acetylation of Lysine 3016 of ATM Activates ATM Kinase Activity

Mol Cell Biol . 2007 Dec 01 ; 27(24) 8502 | DOI : 10.1128/MCB.01382-07

  • Y. Sun
  • et al