IMG-EN-AS-64431-01.jpg
Peptides

IGRP Catalytic Subunit-related Protein (206-214) - 1 mg

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  • Cat.Number : AS-64431
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This peptide corresponds to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice.

Specifications

Chemistry
Sequence one letter code
  • VYLKTNVFL
Sequence three letter code
  • H-Val-Tyr-Leu-Lys-Thr-Asn-Val-Phe-Leu-OH
Molecular Formula
  • C54H85N11O13
Molecular Mass/ Weight
  • 1096.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse

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References

Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice

J Immunol . 2008 Apr 01 ; 180(7) 4458 | DOI : https://doi.org/10.4049/jimmunol.180.7.4458

  • B. Krishnamurthy
  • et al

Developmental control of CD8+ T cell–avidity maturation in autoimmune diabetes

J Clin Invest . 2005 Jul 01 ; 115 1879 | DOI : 10.1172/JCI24219

  • B. Han
  • et al