IGRP Catalytic Subunit-related Protein (206-214) - 1 mg
- Cat.Number : AS-64431
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This peptide corresponds to residues 206–214 of murine islet-specific glucose-6-phosphatase catalytic subunit–related protein (IGRP). This peptide is T cells specific for proinsulin and IGRP induces diabetes in non-obese diabetic (NOD) mice.
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References
Autoimmunity to Both Proinsulin and IGRP Is Required for Diabetes in Nonobese Diabetic 8.3 TCR Transgenic Mice
J Immunol . 2008 Apr 01 ; 180(7) 4458 | DOI : https://doi.org/10.4049/jimmunol.180.7.4458
- B. Krishnamurthy
- et al
Developmental control of CD8+ T cell–avidity maturation in autoimmune diabetes
J Clin Invest . 2005 Jul 01 ; 115 1879 | DOI : 10.1172/JCI24219
- B. Han
- et al