IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide - 1 mg
- Cat.Number : AS-61169
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A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
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References
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