Peptides

KALA - 1 mg

$211.00
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  • Cat.Number : AS-65459
  • Availability :
    In stock

Quantity

KALA is a cationic amphipathic cell-penetrating peptide (CPP). It assumes an a-helix conformation when the pH is 7.5. KALA binds oligonucleotides and disrupts cell membrane; therefore, it can be used as a DNA transfection reagent.

Specifications

Chemistry
Sequence one letter code
  • WEAKLAKALAKALAKHLAKALAKALKACEA
Sequence three letter code
  • Trp-Glu-Ala-Lys-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Ala-Lys-His-Leu-Ala-Lys-Ala-Leu-Ala-Lys-Ala-Leu-Lys-Ala-Cys-Glu-Ala-OH
CAS registry number
  • 187987-64-0
Molecular Formula
  • C144H248N40O35S
Molecular Mass/ Weight
  • 3132.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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References

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

Biochem . 1997 Mar 11 ; 36(10) 3008 | DOI : https://doi.org/10.1021/bi9618474

  • TB. Wyman
  • et al