IMG-EN-AS-24366-01.jpg
Peptides

[Leu31, Pro34]-Neuropeptide Y, human, rat - 1 mg

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  • Cat.Number : AS-24366
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Like neuropeptide Y (NPY) and other peptides of the family, this peptide adopts a folded hairpin structure with the terminal segments in close proximity. An intracerebroventricular injection of NPY or [Leu31, Pro34]-NPY (non-Y2 receptor agonist) given during middle cerebral artery occlusion increases the infarct volume and nitric oxide (NO) overproduction in the rat brain.

Specifications

Chemistry
Sequence one letter code
  • YPSKPDNPGEDAPAEDMARYYSALRHYINLLTRPRY-NH2
Sequence three letter code
  • H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2
CAS registry number
  • 132699-73-1
Molecular Formula
  • C189H284N54O56S
Molecular Mass/ Weight
  • 4240.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, rat

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Citations

Substance P and NPY differentially potentiate ATP and adrenergic stimulated vasopressin and oxytocin release.

Am J Physiol Regul Integr Comp Physiol . 2001 Jan 01 ; 280(1) R69 | DOI : 10.1152/ajpregu.2001.280.1.R69

  • JR. Kapoor
  • CD. Sladek

References

[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

PNAS . 1990 Jan 01 ; 87(1) 182 | DOI : https://doi.org/10.1073/pnas.87.1.182

  • J. Fuhiendorff

Neuronal Cells following Oxygen and Glucose Deprivation

Biomed. Sci. . 2004 Nov 01 ; 11 781 | DOI : https://doi.org/10.1159/000081825

  • SH. Chen
  • et al

Tissue-Specific Regulation of Fat Cell Lipolysis by NPY in 6-OHDA-Treated Rats

Peptides . 1997 Feb 07 ; 18(6) 801 | DOI : https://doi.org/10.1016/S0196-9781(97)00028-4

  • M. Labelle
  • et al