IMG-EN-AS-64638-1-01.jpg
Peptides

[Lys(Ac)18]-Histone H3 (1-21)-GGK(Biotin)-NH2 - 1 mg

$431.00
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  • Cat.Number : AS-64638-1
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    In stock

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This peptide is Histone H3 amino acid residues 1-21. It is acetylated at lysine 18 with a C-terminal GG linker followed by a biotinylated lysine. The acetylation of histone H3 at lysine 18 is used to predict prostrate cancer recurrence and clinical outcome of patients with both lung and kidney cancer. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • ARTKQTARKSTGGKAPR-K(Ac)-QLA-GGK(Biotin)-NH2
Sequence three letter code
  • H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys(Ac)-Gln-Leu-Ala-Gly-Gly-Lys(Biotin)-NH2
Molecular Mass/ Weight
  • 2764.4
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.

PNAS . 2014 Mar 10 ; 111(12) E1072 | DOI : 10.1073/pnas.1319122111

  • C. Das

References

Global Levels of Histone Modifications Predict Prognosis in Different Cancers

Am J Pathol . 2009 May 01 ; 174(5) 1619 | DOI : https://doi.org/10.2353/ajpath.2009.080874

  • DB. Seligson