Peptides

[Lys(Ac)23]-Histone H3 (21-44)-GK(Biotin) - 1 mg

$410.00
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  • Cat.Number : AS-65241-1
  • Availability :
    In stock

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This peptide is histone H3 (21-43) acetylated at Lys23 with a C-terminal GG linker followed by a biotinylated Lys. Acetylation of histone H3 occurs at Lys14 or Lys23 without preference. Lysine acetylation in histone H3 is associated with transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • AT-K(Ac)-AARKSAPATGGVKKPHRYRPG-GK(Biotin)
Sequence three letter code
  • H-Ala-Thr-Lys(Ac)-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2959.6
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.

PNAS . 2014 Mar 10 ; 111(12) E1072 | DOI : 10.1073/pnas.1319122111

  • C. Das

References

Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes

J Biol Chem . 1999 Feb 10 ; 274(9) 5895 | DOI : https://doi.org/10.1074/jbc.274.9.5895

  • P. Grant
  • et al

Pervasive combinatorial modification of histone H3 in human cells

Nat Methods . 2007 May 21 ; 4 487 | DOI : https://doi.org/10.1038/nmeth1052

  • B. Garcia
  • et al