[Lys(Ac)23]-Histone H3 (21-44)-GK(Biotin) - 1 mg
- Cat.Number : AS-65241-1
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This peptide is histone H3 (21-43) acetylated at Lys23 with a C-terminal GG linker followed by a biotinylated Lys. Acetylation of histone H3 occurs at Lys14 or Lys23 without preference. Lysine acetylation in histone H3 is associated with transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
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Citations
Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation.
PNAS . 2014 Mar 10 ; 111(12) E1072 | DOI : 10.1073/pnas.1319122111
- C. Das
References
Expanded Lysine Acetylation Specificity of Gcn5 in Native Complexes
J Biol Chem . 1999 Feb 10 ; 274(9) 5895 | DOI : https://doi.org/10.1074/jbc.274.9.5895
- P. Grant
- et al
Pervasive combinatorial modification of histone H3 in human cells
Nat Methods . 2007 May 21 ; 4 487 | DOI : https://doi.org/10.1038/nmeth1052
- B. Garcia
- et al