IMG-EN-AS-64459-01.jpg
Peptides

[Lys(Me1)4]-Histone H3 (1-21) - 1 mg

$364.00
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  • Cat.Number : AS-64459
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This is a monomethylated lysine at position 4 of the 1-21 amino acid histone H3 peptide. This form of histone methylation is characterized as being enriched around transcription start sites. It’s chromatin mark was also closely correlated to cell-type specific expression of putative gene targets of enhancers. It was also noted from a genome wide study that most potential regulatory elements were enriched only by the mono-methylated version of this histone 3.

Specifications

Chemistry
Sequence one letter code
  • ART-K(Me1)-QTARKSTGGKAPRKQLA
Sequence three letter code
  • H-Ala-Arg-Thr-Lys(Me1)-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-OH
Molecular Mass/ Weight
  • 2268.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Measurement of lysine-specific demethylase-1 activity in the nuclear extracts by flow-injection based time-of-flight mass spectrometry.

J Clin Biochem Nutr . 2015 Feb 13 ; 56(2) 123 | DOI : 10.3164/jcbn.14-99

  • C. Sakane

References

Arg-Gly-Asp-Ser peptide stimulates transforming growth factor-β1 transcription and secretion through integrin activation

FASEB . 2003 Aug 01 ; 17(11) 1 | DOI : https://doi.org/10.1096/fj.02-0785fje

  • R. Ortega-Velazquez
  • et al

Global Mapping of H3K4me1 and H3K4me3 Reveals the Chromatin State-Based Cell Type-Specific Gene Regulation in Human Treg Cells

PLoS One . 2011 Nov 23 ; 6(11) e27770 | DOI : https://doi.org/10.1371/journal.pone.0027770

  • Y. Tian
  • et al