IMG-EN-AS-65449-1-01.jpg
Peptides

[Lys(Me2)27,Lys(Me1)36]-Histone H3 (21-44)-GK(Biotin) - 1 mg

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  • Cat.Number : AS-65449-1
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    In stock

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This peptide is Histone 3, with amino acid residues 21 to 44. It is dimethylated at Lys27 and monomethylated Lys36, with a C-terminal G linker followed by a biotinylated lysine. Histone methylation plays an important role in the regulation of chromatin structure and function.

Specifications

Chemistry
Sequence one letter code
  • ATKAAR-K(Me2)-SAPATGGV-K(Me1)-KPHRYRPG-GK(Biotin)
Sequence three letter code
  • H-Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me2)-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me1)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2959.7
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Quantitative Mass Spectrometry of Histones H3.2 and H3.3 in Suz12-deficient Mouse Embryonic Stem Cells Reveals Distinct, Dynamic Post-translational Modifications at Lys-27 and Lys-36

Mol Cell Proteomics . 2010 May 01 ; 9(5) 838 | DOI : https://doi.org/10.1074/mcp.M900489-MCP200

  • HR. Jung
  • et al