[Lys(Me2)9]-Histone H3 (1-21) - 1 mg
- Cat.Number : AS-65401
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This is histone H3 (1-21) dimethylated at Lys9. Methylation of Lys 9 is associated with transcriptionally silent chromatin. Histone H3 mono- and dimethylated at Lys 9 localize specifically to silent domains within euchromatin while histone H3 trimethylated at this residue localizes to pericentric heterochromatin.
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References
Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains
Mol Cell . 2003 Dec 01 ; 12(6) 1591 | DOI : https://doi.org/10.1016/S1097-2765(03)00479-9
- JC. Rice
- et al