IMG-EN-AS-65401-01.jpg
Peptides

[Lys(Me2)9]-Histone H3 (1-21) - 1 mg

$258.00
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  • Cat.Number : AS-65401
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    In stock

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This is histone H3 (1-21) dimethylated at Lys9. Methylation of Lys 9 is associated with transcriptionally silent chromatin. Histone H3 mono- and dimethylated at Lys 9 localize specifically to silent domains within euchromatin while histone H3 trimethylated at this residue localizes to pericentric heterochromatin.

Specifications

Chemistry
Sequence one letter code
  • ARTKQTAR-K(Me2)-STGGKAPRKQLA
Sequence three letter code
  • H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me2)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-OH
Molecular Mass/ Weight
  • 2282.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains

Mol Cell . 2003 Dec 01 ; 12(6) 1591 | DOI : https://doi.org/10.1016/S1097-2765(03)00479-9

  • JC. Rice
  • et al