IMG-EN-AS-64625-1-01.jpg
Peptides

[Lys(Me3)20]-Histone H4 (1-23)-GGK(Biotin)-NH2 - 1 mg

$431.00
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  • Cat.Number : AS-64625-1
  • Availability :
    In stock

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This peptide is Histone H4 (1-23). It is trimethylated at lysine 20 with a C-terminal GG linker, followed by a biotinylated lysine. Methylation of histone H4 at lysine 20 has a critical role in gene expression, cell cycle progression, and DNA repair. The trimethylation of histone H4 at lysine 20 maintains heterochromatin structures. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • SGRGKGGKGLGKGGAKRHR-K(Me3)-VLR-GGK(Biotin)-NH2
Sequence three letter code
  • H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys(Me3)-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-NH2
Molecular Mass/ Weight
  • 2871.6
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Degrees make all the difference: The multifunctionality of histone H4 lysine 20 methylation

Epigenetics . 2009 Jul 01 ; 4(5) 273 | DOI : https://doi.org/10.4161/epi.4.5.9212

  • Y. Wang
  • S. Jia