IMG-EN-AS-64660-01.jpg
Peptides

NF-kB Inhibitor, SN50 - 1 mg

$237.00
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  • Cat.Number : AS-64660
  • Availability :
    In production

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SN50 is a NF-ΚB cell-permeable inhibitory peptide. it consists of the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor (K-FGF) attached to a NF-kB p50 nuclear localization sequence (NLS). SN50 inhibits translocation of the NF-kB active complex into the nucleus.

Specifications

Chemistry
Sequence one letter code
  • AAVALLPAVLLALLAPVQRKRQKLMP
Sequence three letter code
  • H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH
CAS registry number
  • 213546-53-3
Molecular Formula
  • C129H230N36O29S
Molecular Mass/ Weight
  • 2781.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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Citations

Alkylated dihydroxybenzoic acid as a MALDI matrix additive for hydrophobic peptide analysis.

Anal Chem . 2012 Apr 16 ; 84(9) 4237 | DOI : 10.1021/ac300540r

  • Y. Fukuyama

References

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

J Biol Chem . 1995 Jun 01 ; 270(24) 14255 | DOI : https://doi.org/10.1074/jbc.270.24.14255

  • YZ. Lin
  • et al