IMG-EN-AS-62282-01.jpg
Peptides

Noxa BH3, Peptide 1 - 1 mg

$254.00
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  • Cat.Number : AS-62282
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This peptide belongs to the Bcl-2 family of proteins. Noxa gene encodes a Bcl-2 homology 3 (BH3)-only member of this family; it contains the BH3 region, not other BH domains. When ectopically expressed, Noxa undergoes BH3 motif-dependent localization to mitochondria, it interacts with anti-apoptotic Bcl-2 family members resulting in the activation of caspase-9.

Specifications

Chemistry
Sequence one letter code
  • PAELEVECATQLRRFGDKLNFRQKLL
Sequence three letter code
  • H-Pro-Ala-Glu-Leu-Glu-Val-Glu-Cys-Ala-Thr-Gln-Leu-Arg-Arg-Phe-Gly-Asp-Lys-Leu-Asn-Phe-Arg-Gln-Lys-Leu-Leu-OH
Molecular Formula
  • C136H224N40O39S1
Molecular Mass/ Weight
  • 3075.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Science . 2000 May 12 ; 288(5468) 1053 | DOI : 10.1126/science.288.5468.1053

  • E. Oda
  • et al