Peptides

NRC-16

$182.00
Check your price
  • Cat.Number : AS-65593
  • Availability :
    In stock

Quantity

NRC-16, is a 19 amino acid cationic peptide, derived from witch flounder. NRC-16 shows a potent inhibitory effect against Gram-negative bacteria, Gram-positive bacteria and fungi. When tested for antibiofilm activity with P. aeruginosa strains NRC-16 inhibited biofilm formation with no cytotoxic effects. Since NRC-16 displays antimicrobial and antibiofilm activities with less cytotoxicity, it can be considered for treatment of microbial infections.

Specifications

Chemistry
Sequence one letter code
  • GWKKWLRKGAKHLGQAAIK
Sequence three letter code
  • H-Gly-Trp-Lys-Lys-Trp-Leu-Arg-Lys-Gly-Ala-Lys-His-Leu-Gly-Gln-Ala-Ala-Ile-Lys-OH
Molecular Formula
  • C102H166N32O21
Molecular Mass/ Weight
  • 2176.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Flatfish; flounder

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References

Anti-microbial, anti-biofilm activities and cell selectivity of the NRC-16 peptide derived from witch flounder, Glyptocephalus cynoglossus

Mar Drugs . 2013 May 28 ; 11(6) 1836 | DOI : https://doi.org/10.3390/md11061836

  • R. Gopal
  • et al

Applications of circular dichroism for structural analysis of gelatin and antimicrobial peptides

Int. J. Mol. Sci. . 2012 Mar 08 ; 13(3) 3229 | DOI : 10.3390/ijms13033229

  • R. Gopal
  • et al

Novel antimicrobial peptides derived from flatfish genes

Antimicrob Agents Chemother . 2003 Aug 01 ; 47(8) 2464 | DOI : 10.1128/AAC.47.8.2464-2470.2003

  • A. Patrzykat
  • et al