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Peptides

Orexin B, human - 1 mg

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  • Cat.Number : AS-65573
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Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.

Specifications

Chemistry
Sequence one letter code
  • RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
Sequence three letter code
  • Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
CAS registry number
  • 205640-91-1
Molecular Formula
  • C123H212N44O35S
Molecular Mass/ Weight
  • 2899.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

The physiological role of orexins

Neuroendocrinol Lett . 2005 Aug 01 ; 26(3) 289 | DOI : PMID: 16135995

  • L. Martynska
  • et al