p53 (17-26), FITC labeled - 1 mg
- Cat.Number : AS-62386
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This is amino acids 17 to 26 fragment of p53, fluorescent labeled through an LC spacer. This peptide is the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that come into contact with the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development, FITC (Abs/Em=493 nm/517 nm).
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References
Cellular Uptake of Exogenous Human PDCD5 Protein
J Biol Chem . 2006 Aug 01 ; 281(34) 24803 | DOI : https://doi.org/10.1074/jbc.M600183200
- Y. Wang
- et al
Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells
PNAS . 2001 Oct 23 ; 98(22) 12438 | DOI : https://doi.org/10.1073/pnas.211280698
- M. Kanovsky
- et al