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Peptides

Penetratin - 1 mg

$127.00
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  • Cat.Number : AS-64885
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Penetratin is a cell-penetrating peptide (CPP), also known as a protein transduction domain (PTD), of which the first 16 amino acids are derived from the third helix of the Antennapedia protein homeodomain. Penetratin linked to a phosphodiester oligonucleotide is capable of permeating through neuronal cell membranes and down-regulating genes.

Specifications

Chemistry
Sequence one letter code
  • RQIKIWFQNRRMKWKKGG
Sequence three letter code
  • H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly-OH
Molecular Formula
  • C108H174N36O22S1
Molecular Mass/ Weight
  • 2361
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Drosophila

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Citations

Penetratin improves tumor retention of single-chain antibodies: A novel step toward optimization of radioimmunotherapy of solid tumors.

Cancer Res . 2005 Sep 01 ; 65(17) 7840 | DOI : 10.1158/0008-5472.CAN-05-0662.

  • M. Jain

References

Synthesis, cellular uptake and HIV-1 Tat-dependent trans -activation inhibition activity of oligonucleotide analogues disulphide-conjugated to cell-penetrating peptides

Nucleic Acids Res . 2005 Jan 01 ; 33(1) 27 | DOI : https://doi.org/10.1093/nar/gki142

  • J. Turner
  • et al