IMG-EN-AS-61253-01.jpg
Peptides

Pep-1 - 1 mg

$226.00
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  • Cat.Number : AS-61253
  • Availability :
    In stock

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Pep-1 is one of the synthetic cell-penetrating peptides (CPPs), which has been successfully used to deliver a variety of proteins and other biopharmaceutical macromolecules into cells in a non-disruptive way. It is a CPP with primary amphipathicity (i.e amphipathicity resulting from the amino acid sequence itself, not from the folding structure) that comprises a tryptophan-rich so-called ‘hydrophobic’ domain, a hydrophilic domain derived from an NLS (nuclear localization signal) of SV40 (simian virus 40) large T-antigen, and a spacer between them.

Specifications

Chemistry
Sequence one letter code
  • KETWWETWWTEWSQPKKKRKV
Sequence three letter code
  • Lys-Glu-Thr-Trp-Trp-Glu-Thr-Trp-Trp-Thr-Glu-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val
Molecular Formula
  • C136H195N35O33
Molecular Mass/ Weight
  • 2848.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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References

Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides.

Chembiochem. . 2005 Dec 01 ; 6(12) 2126 | DOI : 10.1002/cbic.200500044

  • R. Fischer
  • et al