IMG-EN-AS-63756-01.jpg
Peptides

Poly-gamma-D-Glutamic Acid Construct - 1 mg

$221.00
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  • Cat.Number : AS-63756
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This peptide is a poly-gamma-D-glutamic acid (DPGA)10 construct that relates to the sequence of the Bacillus anthracis capsule which is composed of gamma DPGA. gamma DPGA is an essential virulence factor of B. anthracis. The capsule inhibits innate host defense through its antiphagocytic action. gamma DPGA is a poor immunogen, but when bound to a carrier protein, it elicits serum antibodies.

Specifications

Chemistry
Sequence one letter code
  • Ac-(γ-e)15-C-NH2
Sequence three letter code
  • Ac-(γ-D-Glu)15-Cys-NH2
Molecular Mass/ Weight
  • 2098.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • synthetic

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References

Additional conjugation methods and immunogenicity of Bacillus anthracis poly-gamma-D-glutamic acid-protein conjugates

Infect Immun . 2006 Aug 01 ; 74(8) 4744 | DOI : 10.1128/IAI.00315-06

  • J. Kubler-Kielb
  • et al