[Pro18]-beta-Amyloid (12-28) - 1 mg
- Cat.Number : AS-65113
- Manufacturer Ref. :
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This peptide is derived from Aβ (12-28), which represents a binding site for apolipoprotein E (apoE). ApoE is a genetically inherited risk factor for Alzheimer’s disease that promotes aggregation of toxic Aβ.
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References
A Synthetic Peptide Blocking the Apolipoprotein E/β-Amyloid Binding Mitigates β-Amyloid Toxicity and Fibril Formation in Vitro and Reduces β-Amyloid Plaques in Transgenic Mice
Am J Pathol . 2004 Sep 01 ; 165(3) 937 | DOI : https://doi.org/10.1016/S0002-9440(10)63355-X
- M. Sadowski
- et al
Residues 17–20 and 30–35 of beta-amyloid play critical roles in aggregation
J Neurosci Res . 2004 Jan 15 ; 75 162 | DOI : https://doi.org/10.1002/jnr.10859
- R. Liu
- et al