Proapoptotic Peptide, (klaklak)2, 5-FAM-labeled - 1 mg
- Cat.Number : AS-62206
- Manufacturer Ref. :
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This is the pro-apoptotic peptide composed of D-amino acids, 5-FAM labeled. This alpha-helical amphipathic peptide is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death.
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References
Selective Apoptotic Killing of Malignant Hemopoietic Cells by Antibody-Targeted Delivery of an Amphipathic Peptide
Cancer Res. . 2005 Mar 01 ; 65(6) 2373 | DOI : 10.1158/0008-5472.CAN-04-2594
- A. Marks
- et al
Reversal of obesity by targeted ablation of adipose tissue
Nat. Med. . 2004 May 09 ; 10(6) 625 | DOI : https://doi.org/10.1038/nm1048
- M. Kolonin
- et al