IMG-EN-AS-62566-01.jpg
Peptides

Rabies Virus Glycoprotein (RVG) - 1 mg

$276.00
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  • Cat.Number : AS-62566
  • Availability :
    In stock

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This peptide is a 29 amino acid fragment derived from rabies virus glycoprotein (RVG). Because neurotropic viruses cross the blood-brain barrier to infect brain cells, the same strategy may be used to enter the central nervous system and deliver siRNA to the brain. This peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.

Specifications

Chemistry
Sequence one letter code
  • YTIWMPENPRPGTPCDIFTNSRGKRASNG
Sequence three letter code
  • H-Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly-OH
Molecular Formula
  • C141H217N43O43S2
Molecular Mass/ Weight
  • 3266.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Rabies virus

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References

Transvascular delivery of small interfering RNA to the central nervous system

Nature . 2007 Jun 17 ; 448 39 | DOI : 10.1038/nature05901

  • P. Kumar
  • et al