IMG-EN-AS-71133-01.jpg
Assay-kits

SensoLyte® 490 MMP-8 Assay Kit Fluorimetric - 1 kit

$804.00
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  • Cat.Number : AS-71133
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Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. MMP-8 (collagenase-2, neutrophil collagenase) is involved in quite a few diseases such as cancer, arthritis and asthma.
The SensoLyte® 490 MMP-8 Assay Kit is a complete assay system designed to continuously analyze MMP activities or to screen MMP-8 inhibitors by using a fluorogenic MMP-8 substrate.

Specifications

Packaging
Kits components
  • Component A: MMP-8 substrate Ex/Em=340 nm/490 nm upon cleavage: 270 µL Component B: EDANS, fluorescence reference standard Ex/Em=340 nm/490 nm: 1 mM, 10 µL Component C: APMA, 4-aminophenylmercuric acetate (Caution: Toxic! Handle with care): 1 M, 100 µL Component D: Assay buffer: 60 mL Component E: Stop solution: 30 mL
Chemistry
UniProt number
  • P22894
Properties
Absorbance (nm)
  • 340
Emission (nm)
  • 490
Storage & stability
Storage Conditions
  • Store all components at -20°C. Protect components A and B from light. Components D and E can be stored at 4 °C for convenience.
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

The inhibitory effects of silver diamine fluoride at different concentrations on matrix metalloproteinases

Dent Mater. . 2012 May 12 ; 28(8) 903 | DOI : 10.1016/j.dental.2012.04.011

  • M.L. Mei