SMAP-18
- Cat.Number : AS-65595
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SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.
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References
Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity
Amino Acids . 2013 Nov 13 ; 46(1) 187 | DOI : 10.1007/s00726-013-1616-8
- B. Jacob
- et al
Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis
Antimicrob Ag Chemother . 2001 Oct 01 ; 45(10) 2838 | DOI : https://doi.org/10.1128/AAC.45.10.2838-2844.2001
- L. Saiman