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Peptides

SMAP-18

$182.00
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  • Cat.Number : AS-65595
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SMAP-18 is a 18-amino acid residue peptide amide which is a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) displays extremely high antimicrobial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. SMAP-18 displays much higher cell selectivity as compared to parental SMAP-29 because of its decreased hemolytic activity and retained antimicrobial activity.

Specifications

Chemistry
Sequence one letter code
  • RGLRRLGRKIAHGVKKYG-NH2
Sequence three letter code
  • H-Arg-Gly-Leu-Arg-Arg-Leu-Gly-Arg-Lys-Ile-Ala-His-Gly-Val-Lys-Lys-Tyr-Gly-NH2
Molecular Formula
  • C91H163N36O20
Molecular Mass/ Weight
  • 2064.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • sheep

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References

Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity

Amino Acids . 2013 Nov 13 ; 46(1) 187 | DOI : 10.1007/s00726-013-1616-8

  • B. Jacob
  • et al

Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis

Antimicrob Ag Chemother . 2001 Oct 01 ; 45(10) 2838 | DOI : https://doi.org/10.1128/AAC.45.10.2838-2844.2001

  • L. Saiman