Spike protein (S2) SARS-CoV-2 substrate - 0.1 mg
- Cat.Number : AS-65601
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This peptide sequence represents a second furin-like cleavage site of the Spike (S) protein also thought to participate in the process of viral entry into host cell. The sequence at the S2 site (KR↓SF) contains two basic residues (P1 and P2) and a hydrophobic P3 residue. This site is identical between the SARS-CoV-2 and SARS-CoV. This peptide has been labeled with QXL®520 and 5-FAM.
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References
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
Antiviral Res. . 2020 Apr 01 ; 176 104742 | DOI : https://doi.org/10.1016/j.antiviral.2020.104742
- B. Coutard
- et al