Substance P
- Cat.Number : AS-24279
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Substance P (SP) is an important neuropeptide belonging to the tachykinin family. It acts as a neurotransmitter and neuromodulator. It is closely related to neurokinin A, both originating from the same precursor preprotachykinin A. It is released from the terminals of sensory nerves and is involved in inflammation and pain processes.
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Citations
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin
Proc Natl Acad Sci U S A. . 2013 May 20 ; 110(23) 9529 | DOI : 10.1073/pnas.1219004110
- RC. Meyer
Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii
J Biol Chem. . 2008 Aug 07 ; 283(43) 29186 | DOI : 10.1074/jbc.M802366200
- AJ. O'Donoghue
References
Analysis of fluorescently labeled substance P analogs: binding, imaging and receptor activation
BMC Chem Biol . 2001 Jun 13 ; 1 1
- V. Bennett
- M. Simmons
The conformation of substance P in lipid environments
Biophys J . 1996 Apr 01 ; 70(4) 1716 | DOI : https://doi.org/10.1016/S0006-3495(96)79734-5
- DA. Keire
- TG. Fletcher