Peptides

Temporin L, amide - 1 mg

  • Cat.Number : AS-64836
  • Availability :
    In stock

Quantity

Temporin L is a hydrophobic peptide amide derived from the frog Rana temporaria. This peptide penetrates the hydrophobic core of the cell membrane to penetrate and disrupt the lipid bilayer. Temporin L enhances Temporin A and Temporin B activity by preventing their oligomerization to Lipopolysaccharide (LPS), allowing them to bypass LPS and access the cytoplasmic membrane. This peptide is active against Gram-positive and Gram-negative bacteria, including B. megaterium and E. coli.

Specifications

Chemistry
Sequence one letter code
  • FVQWFSKFLGRIL-NH2
Sequence three letter code
  • H-Phe-Val-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg-Ile-Leu-NH2
Molecular Formula
  • C83H122N20O15
Molecular Mass/ Weight
  • 1640.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • frog

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References

A Synergism between Temporins toward Gram-negative Bacteria Overcomes Resistance Imposed by the Lipopolysaccharide Protective Layer

J Biol Chem . 2006 Sep 01 ; 281(39) 28565 | DOI : https://doi.org/10.1074/jbc.M606031200

  • Y. Rosenfeld
  • et al

Binding of the Antimicrobial Peptide Temporin L to Liposomes Assessed by Trp Fluorescence

J Biol Chem . 2002 Jul 01 ; 277(28) 25170 | DOI : https://doi.org/10.1074/jbc.M203186200

  • H. Zhao
  • et al